SCHEMBL2778024

SCHEMBL2778024

C/C(=N\OCc1cccc(C)n1)c1ccc(Cl)c(CNC(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
PPARG P37231 6/20 0.40
PPARA Q07869 4/20 0.40
MEN1 O00255 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRD1 P41143 1/20 0.39
KMT2A Q03164 1/20 0.39
HPGD P15428 1/20 0.37
PTGES O14684 1/20 0.36
ADORA2A P29274 1/20 0.36
DPP4 P27487 1/20 0.36
S1PR1 P21453 2/20 0.35
S1PR3 Q99500 1/20 0.35
PPARD Q03181 1/20 0.35
BRD4 O60885 1/20 0.35
BRD2 P25440 1/20 0.35
BRD3 Q15059 1/20 0.35
BRDT Q58F21 1/20 0.35
SORT1 Q99523 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2744761 1.00 NPC1 (0.41) NPC1RAB9APPARGPPARAMEN1
SCHEMBL2744757 1.00 NPC1 (0.41) NPC1RAB9APPARGPPARAMEN1
SCHEMBL4667781 0.94 NPSR1 (0.40) NPC1RAB9APPARGPPARAMEN1
SCHEMBL4667786 0.94 NPSR1 (0.40) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL29935941 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL3228377 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL18875 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL557610 0.93 NPC1 (0.39) NPC1RAB9APPARGPPARAMEN1
Pyribencarb SCHEMBL557599 0.92 NPC1 (0.38) NPC1RAB9APPARGPPARAMEN1
SCHEMBL12855963 0.87 NPC1 (0.36) NPC1RAB9APPARGPPARAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115885983-A Aqueous suspension pesticide composition and method for spreading the same 组合化学工业株式会社 2023-04-04 CN disclosed
US-20200253200-A1 DELIVERY OF PARAFFINIC OIL-CONTAINING COMPOSITIONS TO ROOT TISSUE OF PLANTS SUNCOR ENERGY INC (CA) 2020-08-13 US disclosed
US-10701939-B2 Aqueous suspension agrochemical composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2020-07-07 US disclosed
US-10440949-B2 Aqueous agrochemical suspension composition and dispersal method therefor KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2019-10-15 US disclosed
EP-2713749-B1 PARAFFINIC OIL-IN-WATER EMULSIONS FOR CONTROLLING INFECTION OF CROP PLANTS BY FUNGAL PATHOGENS SUNCOR ENERGY INC (CA) 2019-05-22 EP disclosed
US-20180343866-A1 AQUEOUS SUSPENSION AGROCHEMICAL COMPOSITION KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2018-12-06 US disclosed
EP-2723177-B1 DELIVERY OF PARAFFINIC OIL-CONTAINING COMPOSITIONS TO ROOT TISSUE OF PLANTS SUNCOR ENERGY INC (CA) 2017-09-06 EP disclosed
US-20160302416-A1 Methods for Increasing Resistance of Plants to Abiotic Stresses SUNCOR ENERGY INC. (CA) 2016-10-20 US disclosed
US-9451773-B2 Paraffinic oil-in-water emulsions for controlling infection of crop plants by fungal pathogens SUNCOR ENERGY INC. (CA) 2016-09-27 US disclosed
US-20140256556-A1 DELIVERY OF PARAFFINIC OIL-CONTAINING COMPOSITIONS TO ROOT TISSUE OF PLANTS SUNCOR ENERGY INC. (CA) 2014-09-11 US disclosed
EP-1887868-B1 FUNGICIDAL ACTIVE INGREDIENT COMBINATION BAYER CROPSCIENCE AG (DE) 2009-02-18 EP disclosed
EP-1871744-B1 NEW HETEROCYCLYLETHYLBENZAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2009-01-07 EP disclosed
EP-1888535-B1 NEW HETEROCYCLYLETHYLBENZAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2008-11-19 EP disclosed
WO-2008131901-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2008-11-06 WO disclosed
EP-1856054-B1 PYRAZOLYLCARBOXANILIDES BAYER CROPSCIENCE AG (DE) 2008-09-17 EP disclosed
EP-1887868-A1 FUNGICIDAL ACTIVE INGREDIENT COMBINATION Bayer CropScience Aktiengesellschaft (DE) 2008-02-20 EP disclosed
WO-2006125618-A9 FUNGICIDAL ACTIVE INGREDIENT COMBINATION BAYER CROPSCIENCE AG (DE) 2008-01-31 WO disclosed
EP-1792901-A1 N-(1-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES Bayer CropScience S.A. (FR) 2007-06-06 EP disclosed
EP-1787981-A1 New N-phenethylcarboxamide derivatives Bayer CropScience S.A. (FR) 2007-05-23 EP disclosed
WO-2006125618-A1 FUNGICIDAL ACTIVE INGREDIENT COMBINATION BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256556-A1 DELIVERY OF PARAFFINIC OIL-CONTAINING COMPOSITIONS TO ROOT TISSUE OF PLANTS CROCC, CUTA, NACA NPC1 184/4885RAB9A 3739/4885PPARG 1264/4885
US-20180343866-A1 AQUEOUS SUSPENSION AGROCHEMICAL COMPOSITION SPIN2B, PIR, SMARCC2 NPC1 4880/4885RAB9A 3941/4885PPARG 669/4885
US-10701939-B2 Aqueous suspension agrochemical composition SPIN2B, PIR, SMARCC2 NPC1 4880/4885RAB9A 3941/4885PPARG 669/4885
US-20160302416-A1 Methods for Increasing Resistance of Plants to Abiotic Stresses PRDX6, PRDX2, GPX4 NPC1 2184/4885RAB9A 4368/4885PPARG 459/4885
US-20200253200-A1 DELIVERY OF PARAFFINIC OIL-CONTAINING COMPOSITIONS TO ROOT TISSUE OF PLANTS ABCB1, ABCC1, CROCC NPC1 122/4885RAB9A 4151/4885PPARG 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.