Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14654862 | 1.00 | CYP2C19 (0.42) | CYP2C19TRPA1ALDH1A1LMNAGSR | |
| SCHEMBL5560718 | 0.83 | TRPA1 (0.44) | CYP2C19TRPA1ALDH1A1LMNAKDM4E | |
| SCHEMBL3785691 | 0.79 | TRPA1 (0.38) | CYP2C19TRPA1ALDH1A1LMNAGSR | |
| SCHEMBL6016109 | 0.79 | CYP2C19 (0.39) | CYP2C19ALDH1A1HTR2ATAAR1KDM4E | |
| SCHEMBL15951418 | 0.78 | TRPA1 (0.37) | CYP2C19TRPA1ALDH1A1LMNAHTR2A | |
| SCHEMBL4553372 | 0.77 | TAAR1 (0.52) | CYP2C19HTR2ATAAR1CYP2D6CYP3A4 | |
| SCHEMBL9921450 | 0.77 | LMNA (0.46) | CYP2C19TRPA1ALDH1A1LMNAHTR2A | |
| SCHEMBL15393365 | 0.77 | CYP2C19 (0.38) | CYP2C19TRPA1ALDH1A1HTR2ATAAR1 | |
| SCHEMBL19233902 | 0.77 | TAAR1 (0.52) | CYP2C19HTR2ATAAR1CYP2D6CYP3A4 | |
| SCHEMBL11773608 | 0.77 | CYP2C19 (0.42) | CYP2C19ALDH1A1HTR2ATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434604-A4 | 4-HALOETHENYLPHENYL TROPANE:SEROTONIN TRANSPORTER IMAGING AGENTS | UNIV EMORY (US) | 2008-01-09 | — | — | EP | disclosed |
| US-6843979-B2 | 4-haloethenylphenyl tropane:serotonin transporter imaging agents | EMORY UNIVERSITY (US) | 2005-01-18 | — | — | US | disclosed |
| EP-1212103-B1 | 4-FLUOROALKYL-3-HALOPHENYL NORTROPANES | UNIV EMORY (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1434604-A2 | 4-HALOETHENYLPHENYL TROPANE:SEROTONIN TRANSPORTER IMAGING AGENTS | Emory University (US) | 2004-07-07 | — | — | EP | disclosed |
| CN-1143870-C | Impact modifier for amorphous aromatic polyester | ��������ķ������ | 2004-03-31 | — | — | CN | disclosed |
| EP-1212103-A4 | 4-FLUOROALKYL-3-HALOPHENYL NORTROPANES | UNIV EMORY (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2003031452-A2 | 4-HALOETHENYLPHENYL TROPANE:SEROTONIN TRANSPORTER IMAGING AGENTS | EMORY UNIVERSITY (US) | 2003-04-17 | — | — | WO | disclosed |
| US-20020099184-A1 | 4-Haloethenyphenyl tropane:serotonin transporter imaging agents | ENERGY, UNITED STATES DEPARTMENT OF | 2002-07-25 | — | — | US | disclosed |
| EP-1212103-A1 | 4-FLUOROALKYL-3-HALOPHENYL NORTROPANES | Emory University (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6399042-B1 | HALOGEN RADIOLABELED IMAGING AGENTS FOR VISUALIZING THE LOCATION AND DENSITY OF SEROTONIN TRANSPORTER BY POSITRON EMISSION TOMOGRAPHY | EMORY UNIVERSITY | 2002-06-04 | — | — | US | disclosed |
| CN-1302830-A | Impact modifier concentrate for amorphous aromatic polyester | ROHM & HAAS (US) | 2001-07-11 | — | — | CN | disclosed |
| CN-1288912-A | Modified phenylethylene-acrylonitrile resin blended composition and product formed therefrom | ROHM & HAAS (US) | 2001-03-28 | — | — | CN | disclosed |
| WO-2000064491-A1 | 4-FLUOROALKYL-3-HALOPHENYL NORTROPANES | EMORY UNIVERSITY (US) | 2000-11-02 | — | — | WO | disclosed |
| CN-1233670-A | Impact modifier for amorphous aromatic polyester | ROHM & HAAS (US) | 1999-11-03 | — | — | CN | disclosed |
| EP-0410466-B1 | Substituted phenylalkylimidazole compounds | HODOGAYA CHEMICAL CO LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0470282-B1 | Agricultural or horticultural fungicide | HODOGAYA CHEMICAL CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0470282-A1 | Agricultural or horticultural fungicide | HODOGAYA CHEMICAL CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |
| US-5057533-A | 1-((2,4-Di(cl-),3-(ch3-)phenyl)-ch(-ch2-ch2-ch3)-)imidazole | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| US-5057145-A | PHENYLALKYLIMIDAZOLE COMPOUNDS AS FUNGICIDES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0410466-A2 | Substituted phenylalkylimidazole compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099184-A1 | 4-Haloethenyphenyl tropane:serotonin transporter imaging agents | SLC6A4, SLC6A2, SLC6A3 | CYP2C19 1298/4885TRPA1 458/4885ALDH1A1 2667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.