SCHEMBL28402016

SCHEMBL28402016

CCCC=C(OC(C)=O)c1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
HDAC3 O15379 3/20 0.42
HDAC1 Q13547 3/20 0.42
HDAC2 Q92769 3/20 0.42
HDAC4 P56524 2/20 0.42
HDAC7 Q8WUI4 2/20 0.42
HDAC10 Q969S8 2/20 0.42
HDAC11 Q96DB2 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
HDAC9 Q9UKV0 2/20 0.42
HDAC5 Q9UQL6 2/20 0.42
GSK3B P49841 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4667898 0.80 CES2 (0.53) CES2CES1CA1CA2HDAC3
SCHEMBL9943776 0.74 CA1 (0.51) NR1I2TAS1R3TAS1R1CES2CES1
SCHEMBL10357853 0.71 NQO2 (0.47) NR1I2TAS1R3TAS1R1CES2CES1
SCHEMBL4998485 0.71 CA1 (0.67) NR1I2CES2CES1CA1CA2
SCHEMBL23966514 0.71 ALDH1A1 (0.50) TAS1R3TAS1R1HDAC3HDAC1HDAC2
SCHEMBL20273283 0.70 GPR52 (0.67) MAPTCYP1A2CYP3A4CYP2C19KMT2A
SCHEMBL4254809 0.70 THRB (0.47) TAS1R3TAS1R1MAPTKMT2A
SCHEMBL28586063 0.70 CA1 (0.64) CES2CES1CA1CA2GSK3B
Butane SCHEMBL10982980 0.70 KMT2A (0.66) NR1I2CES2CES1CA1CA2
SCHEMBL9333553 0.69 CES1 (0.44) CES2CES1MAPTCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111122747-A Method for analyzing sensitized aromatic substances in cosmetics 汕头出入境检验检疫局检验检疫技术中心 2020-05-08 CN disclosed