SCHEMBL46682

SCHEMBL46682

CC(C)(C)OC(=O)N1CCN(CCN)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
ALOX15 P16050 1/20 0.45
TLR8 Q9NR97 1/20 0.45
ACKR3 P25106 2/20 0.44
HPGD P15428 1/20 0.43
EPHX2 P34913 1/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
RECQL P46063 1/20 0.41
EPHX1 P07099 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12644325 1.00 USP2 (0.50) USP2SMN1; SMN2CHRM2CHRM4CHRM1
Ammonia Solution, Strong SCHEMBL208691 0.98 USP2 (0.49) USP2SMN1; SMN2CHRM2CHRM4CHRM1
Trifluoroacetic Acid SCHEMBL27830007 0.91 USP2 (0.43) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL7687 0.90 TLR8 (0.48) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL6221438 0.90 TLR8 (0.48) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL8242595 0.89 USP2 (0.61) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL943825 0.89 TLR8 (0.47) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL12264373 0.87 TLR8 (0.47) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL29263655 0.87 TLR8 (0.47) USP2SMN1; SMN2CHRM2CHRM4CHRM1
SCHEMBL18751236 0.87 TLR8 (0.47) USP2SMN1; SMN2CHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 813 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036730-A Gαq/11 protein inhibitor with purine skeleton, and preparation method and application thereof 中山大学 2026-05-15 CN claimed
CN-110157251-B Curing agent composition and coating composition comprising same KCC公司 2022-04-01 CN claimed
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
CN-119019389-B 7-Azaindole compound and synthetic method and application thereof SICHUAN UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-122029157-A Bilobalide derivatives for the treatment of neurological diseases and cancers 香港中文大学 2026-05-12 CN disclosed
EP-4304842-B1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC (CH) 2026-05-06 EP disclosed
US-20260115297-A1 HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF HPK1 ICAHN SCHOOL MED MOUNT SINAI (US) 2026-04-30 US disclosed
EP-4731611-A1 TARGETED DEGRADERS OF HIV-1 NEF FOR THE TREATMENT OF HIV DISEASE UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-04-29 EP disclosed
US-20260109678-A1 SUBSTITUTED PHENOTHIAZINES AS FERROPTOSIS INHIBITORS UNIVERSITEIT ANTWERPEN (BE) 2026-04-23 US disclosed
EP-4724435-A1 BIFUNCTIONAL AZINES CONJOGATES AS SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF Nurix Therapeutics, Inc. (US) 2026-04-15 EP disclosed
US-4812452-A ANTIARRHYTHMIA AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1989-03-14 US disclosed
US-4812451-A ANTIARRHYTHMIA AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1989-03-14 US disclosed
US-4810703-A ANTIARRHYTHMIA A. H. ROBINS COMPANY, INCORPORATED (US) 1989-03-07 US disclosed
US-4594343-A FOR DEEP FAT FRYING VAT OIL; REMOVING CONTAMINANTS; RESTAURANTS A.H. ROBINS COMPANY, INCORPORATED, A DE CORP. 1986-06-10 US disclosed
EP-0178947-A2 1-[(Aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-alpha,alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles A.H. ROBINS COMPANY, INCORPORATED (US) 1986-04-23 EP disclosed
US-4547514-A Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity A. H. ROBINS COMPANY, INCORPORATED (US) 1985-10-15 US disclosed
EP-0147909-A1 Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity A.H. ROBINS COMPANY, INCORPORATED (US) 1985-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115297-A1 HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF HPK1 TTK, ITK, CLK1 USP2 337/4885SMN1; SMN2 4005/4885CHRM2 2780/4885
US-20260109678-A1 SUBSTITUTED PHENOTHIAZINES AS FERROPTOSIS INHIBITORS AIFM2, HMOX1, ARG2 USP2 3729/4885SMN1; SMN2 2096/4885CHRM2 2518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.