Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157262 | 0.87 | ALDH1A1 (0.34) | GPBAR1RORC | |
| SCHEMBL4149344 | 0.86 | RORC (0.43) | RORC | |
| SCHEMBL4636412 | 0.84 | CES2 (0.34) | GPBAR1RORC | |
| SCHEMBL4636710 | 0.83 | CYP11B1 (0.33) | CYP11B1GPBAR1CYP11B2DHODH | |
| SCHEMBL4158854 | 0.80 | RORC (0.35) | GPBAR1RORC | |
| SCHEMBL4636222 | 0.79 | CES2 (0.35) | GPBAR1RORCDHODH | |
| SCHEMBL4164252 | 0.76 | RORC (0.40) | RORC | |
| SCHEMBL4154435 | 0.76 | RORC (0.36) | GPBAR1RORC | |
| SCHEMBL4162997 | 0.76 | RORC (0.46) | RORC | |
| SCHEMBL4636754 | 0.75 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |