SCHEMBL4668951

SCHEMBL4668951

C=C1c2ccccc2CC2=CC=CCC12

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.32
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1646181 0.81 MAOA (0.40) MAOABCHECES1ALDH1A1CYP1A2
SCHEMBL12668087 0.68 PGR (0.33) ALDH1A1
SCHEMBL11775155 0.67
SCHEMBL3294807 0.66 ADRA1A (0.36) CYP1A2
SCHEMBL18403517 0.62 MAOB (0.38) MAOA
SCHEMBL21538713 0.59
SCHEMBL4668953 0.59 MAOA (0.56) MAOABCHECES1ALDH1A1CYP1A2
Fluorene SCHEMBL27617355 0.58 MAOA (0.62) MAOABCHECES1ALDH1A1CYP1A2
Fluorene SCHEMBL27915067 0.58 MAOA (0.62) MAOABCHECES1ALDH1A1CYP1A2
Fluorene SCHEMBL10905010 0.58 MAOA (0.62) MAOABCHECES1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108129440-B Method for synthesizing chiral chromene derivative 中国科学院大连化学物理研究所 2021-05-28 CN claimed
US-20140030653-A1 COATING COMPOSITIONS FOR PHOTOLITHOGRAPHY ROHM & HAAS ELECT MAT (US) 2014-01-30 US disclosed
US-8455178-B2 Coating compositions for photolithography ROHM AND HAAS ELECTRONIC MATERIALS LLP (US) 2013-06-04 US disclosed
EP-1906249-A2 Antireflective coating compositions for photolithography Rohm and Haas Electronic Materials, L.L.C. (US) 2008-04-02 EP disclosed
US-20080073754-A1 Coating compositions for photolithography ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2008-03-27 US disclosed