Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FCGR3B | O75015 | 1/20 | 0.32 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.32 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692969 | 0.97 | PRSS1 (0.39) | ALDH1A1TDP1TSHRPRSS1F2 | |
| SCHEMBL855272 | 0.97 | PRSS1 (0.39) | ALDH1A1TDP1TSHRPRSS1F2 | |
| SCHEMBL484008 | 0.86 | TDP1 (0.40) | ALDH1A1TDP1TSHRPRSS1PSMD14 | |
| SCHEMBL9022771 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRMAPK1RECQL | |
| SCHEMBL34106 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRPSMD14CYP3A4 | |
| SCHEMBL9490421 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRPRSS1F2 | |
| Hydrochloric Acid SCHEMBL11701613 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRPRSS1F2 | |
| SCHEMBL11934947 | 0.81 | PRSS1 (0.42) | ALDH1A1TDP1TSHRPRSS1F2 | |
| SCHEMBL10565565 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRPSMD14CYP3A4 | |
| SCHEMBL3857753 | 0.80 | PRSS1 (0.42) | ALDH1A1PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852135-B2 | Oxidative dyeing composition for keratin fibres and dyeing method employing it | OREAL (FR) | 2008-03-19 | — | — | EP | claimed |