SCHEMBL855272

SCHEMBL855272

Nc1ccc(NCCCCN(CCO)c2ccc(N)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 8/20 0.39
F2 P00734 2/20 0.38
PRSS2 P07478 2/20 0.38
PRSS3 P35030 2/20 0.38
TMPRSS6 Q8IU80 2/20 0.38
ST14 Q9Y5Y6 2/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
PSMD14 O00487 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
RECQL P46063 1/20 0.37
GFER P55789 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
APP P05067 1/20 0.36
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5692969 1.00 PRSS1 (0.39) PRSS1F2PRSS2PRSS3TMPRSS6
SCHEMBL4668959 0.97 ALDH1A1 (0.42) PRSS1F2PRSS2PRSS3TMPRSS6
SCHEMBL484008 0.89 TDP1 (0.40) PRSS1ALDH1A1TSHRTDP1PSMD14
SCHEMBL34106 0.85 ALDH1A1 (0.48) ALDH1A1TSHRTDP1PSMD14CYP3A4
SCHEMBL9490421 0.84 ALDH1A1 (0.43) PRSS1F2PRSS2PRSS3TMPRSS6
Hydrochloric Acid SCHEMBL11701613 0.84 ALDH1A1 (0.47) PRSS1F2PRSS3ALDH1A1TSHR
SCHEMBL11934947 0.83 PRSS1 (0.42) PRSS1F2PRSS2PRSS3TMPRSS6
SCHEMBL3857753 0.83 PRSS1 (0.42) PRSS1F2PRSS2PRSS3TMPRSS6
SCHEMBL14940571 0.82 ALDH1A1 (0.48) ALDH1A1TSHRTDP1PSMD14CYP3A4
SCHEMBL23839781 0.80 ALDH1A1 (0.47) ALDH1A1TSHRTDP1PSMD14CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473025-B1 Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer OREAL (FR) 2012-03-28 EP claimed
EP-0790818-B1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME OREAL (FR) 2001-05-30 EP claimed
CN-120035427-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-23 CN disclosed
CN-119968189-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-05-09 CN disclosed
CN-119894486-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-25 CN disclosed
CN-119855579-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-18 CN disclosed
CN-119836282-A Composition for lightening keratin fibres and method for lightening keratin fibres using said composition 莱雅公司 2025-04-15 CN disclosed
CN-118488824-A Compositions, methods and kits for altering hair color 欧莱雅 2024-08-13 CN disclosed
CN-118401231-A Composition for keratin fibres 莱雅公司 2024-07-26 CN disclosed
US-12042556-B2 Oxidative hair cream composition containing polymeric colorant MILLIKEN & COMPANY (US) 2024-07-23 US disclosed
EP-4362891-A1 COMPOSITION COMPRISING AT LEAST ONE PARTICULAR COUPLER, AT LEAST ONE PARTICULAR OXIDATION BASE, AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ANIONIC POLYSACCHARIDE L'OREAL (FR) 2024-05-08 EP disclosed
CN-105828884-B Packaging article comprising an envelope and an anhydrous dye composition comprising an oxidation dye, use thereof and process for dyeing keratin fibres 莱雅公司 2022-04-08 CN disclosed
CN-114286712-A Composition for dyeing keratin fibres 莱雅公司 2022-04-05 CN disclosed
CN-114269320-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-01 CN disclosed
US-11266589-B2 Hair dyeing composition comprising an oxidation dye, a scleroglucan gum, and an alkylpolyglycoside L'OREAL (FR) 2022-03-08 US disclosed
CN-108472232-B Composition for dyeing hair comprising an oxidation base of the p-phenylenediamine type and a coupler of 2-amino-5-ethylphenol 莱雅公司 2022-02-18 CN disclosed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-6551359-B1 Laccase, an oxidation color dye, and solvent selected from among certain polyols and their ethers; dyeing methods and kits L'OREAL S.A. (FR) 2003-04-22 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
US-6090159-A READY-TO-USE OXIDATION DYEING COMPOSITION COMPRISING AN OXIDATION BASE, SARCOSINE OXIDASE AS OXIDIZER, AND AT LEAST ONE DONOR FOR THE ENZYME; STRONGER COLORATION, NO BLEACHING L'OREAL (FR) 2000-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11266589-B2 Hair dyeing composition comprising an oxidation dye, a scleroglucan gum, and an alkylpolyglycoside KRT18, OGG1, ALPG PRSS1 2922/4885F2 3491/4885PRSS2 1955/4885
US-12042556-B2 Oxidative hair cream composition containing polymeric colorant LPO, COX5A, GPX4 PRSS1 2530/4885F2 3752/4885PRSS2 3023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.