Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799902 | 0.87 | KMT2A (0.49) | MEN1KMT2ANPC1TP53HPGD | |
| SCHEMBL4145291 | 0.77 | POLB (0.44) | MEN1KMT2ANPC1TP53ALDH1A1 | |
| SCHEMBL5063069 | 0.76 | KMT2A (0.63) | MEN1KMT2ANPC1TP53HPGD | |
| SCHEMBL4146318 | 0.73 | CNR1 (0.35) | TP53ALDH1A1RORCMAPTSMN1; SMN2 | |
| SCHEMBL4884821 | 0.72 | CNR1 (0.59) | MEN1KMT2ATP53HPGDALDH1A1 | |
| SCHEMBL4668903 | 0.72 | CNR1 (0.54) | NPC1SMN1; SMN2 | |
| SCHEMBL5057587 | 0.72 | CNR1 (0.61) | MEN1KMT2ANPC1TP53HPGD | |
| SCHEMBL4146312 | 0.72 | CNR1 (0.46) | TP53HPGDMAPTSMN1; SMN2 | |
| SCHEMBL5057283 | 0.72 | CNR1 (0.63) | MEN1KMT2ANPC1TP53HPGD | |
| SCHEMBL5062729 | 0.71 | MEN1 (0.62) | MEN1KMT2ANPC1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937677-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | Arcadia Pharmaceuticals Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007047737-A1 | CB-1 MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2007-04-26 | — | — | WO | disclosed |