SCHEMBL4669386

SCHEMBL4669386

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nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 2/20 0.35
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
TGFBR1 P36897 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4669389 0.79 LMNA (0.34) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL9235255 0.79 LMNA (0.44) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL18259766 0.78 TGFBR1 (0.39) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL10770007 0.78 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL812714 0.78 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL468790 0.78 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL468705 0.78 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL468798 0.78 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL27182003 0.78 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1
SCHEMBL11225324 0.78 PDE4A (0.50) LMNAL3MBTL1KDM4EPDE4ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6977285-B2 Oligomers containing N-acetyl glucosamine (NAG) COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-12-20 US claimed
EP-1699833-B1 OLIGOMERS CONTAINING N-ACETYL GLUCOSAMINE COUNCIL SCIENT IND RES (IN) 2008-09-24 EP disclosed
EP-1699833-A1 OLIGOMERS CONTAINING N-ACETYL GLUCOSAMINE Council of Scientific and Industrial Research (IN) 2006-09-13 EP disclosed
EP-1615940-A1 POLYMERIZABLE MONOMERS AND PROCESS OF PREPARATION THEREOF Council of Scientific and Industrial Research (IN) 2006-01-18 EP disclosed
US-6977285-B2 Oligomers containing N-acetyl glucosamine (NAG) COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-12-20 US disclosed
US-20050222326-A1 OLIGOMERS CONTAINING N-ACETYL GLUCOSAMINE (NAG) COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2005-10-06 US disclosed
WO-2005063833-A1 OLIGOMERS CONTAINING N-ACETYL GLUCOSAMINE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-07-14 WO disclosed
WO-2004087725-A1 POLYMERIZABLE MONOMERS AND PROCESS OF PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-10-14 WO disclosed
US-20040192905-A1 Polymerizable monomers and process of preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL (IN) 2004-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192905-A1 Polymerizable monomers and process of preparation thereof FUT6, B3GNT2, ALG1 LMNA 409/4885L3MBTL1 382/4885KDM4E 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.