SCHEMBL4669598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4668729	0.85	GRM5 (0.46)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19
	SCHEMBL4900008	0.76	GRM5 (0.45)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19
	SCHEMBL4668361	0.75	GRM5 (0.47)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19
	SCHEMBL4886864	0.73	GRM5 (0.43)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19
	SCHEMBL12896679	0.72	CHRM1 (0.46)	GRM5CHRM1SMN1; SMN2HTTMEN1
	SCHEMBL14081574	0.72	GRM5 (0.53)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19
	SCHEMBL2877584	0.71	CHRM2 (0.44)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19
	SCHEMBL4983052	0.70	L3MBTL1 (0.56)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19
	SCHEMBL15304325	0.68	GRM5 (0.49)	GRM5ALDH1A1CHRM1TDP1CHRM4
	SCHEMBL5247939	0.67	GRM5 (0.47)	GRM5ALDH1A1CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.