Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475871 | 0.87 | LMNA (0.46) | ESR1PDCD1ESR2CD274LMNA | |
| SCHEMBL29352459 | 0.87 | LMNA (0.46) | ESR1PDCD1ESR2CD274LMNA | |
| SCHEMBL2336888 | 0.87 | LMNA (0.46) | ESR1PDCD1ESR2CD274LMNA | |
| SCHEMBL153358 | 0.82 | ADRB2 (0.62) | ADRB2ESR1PDCD1ESR2CD274 | |
| SCHEMBL29486483 | 0.81 | TYR (0.40) | ESR1PDCD1ESR2CD274LMNA | |
| SCHEMBL441363 | 0.81 | TYR (0.40) | ESR1PDCD1ESR2CD274LMNA | |
| Ammonia Solution, Strong SCHEMBL7978172 | 0.79 | ADRB2 (0.59) | ADRB2ESR1PDCD1ESR2CD274 | |
| SCHEMBL15423680 | 0.78 | ADRB2 (0.52) | ADRB2ESR1PDCD1ESR2CD274 | |
| SCHEMBL9955312 | 0.78 | BRD4 (0.41) | ADRB2CYP3A4TSHRMAPK1HIF1A | |
| Methylamine SCHEMBL6499701 | 0.77 | ADRB2 (0.64) | ADRB2ESR1PDCD1ESR2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | DAICEL CHEMICAL INSDUSTRIES, LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1967505-A1 | Process for the preparation of substituted phenols | Daicel Chemical Industries, Ltd. (JP) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221369-A1 | Process for the preparation of substituted phenols | CYP1A1, NOX1, ROS1 | ADRB2 207/4885CYP3A4 153/4885ESR1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.