SCHEMBL30475871

SCHEMBL30475871

Cc1ccc(C(C)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
PTGS1 P23219 2/20 0.44
TRPA1 O75762 1/20 0.44
CACNA1C Q13936 1/20 0.44
ALDH1A1 P00352 2/20 0.42
ESR1 P03372 1/20 0.42
PDCD1 Q15116 1/20 0.42
ESR2 Q92731 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.36
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
ACHE P22303 1/20 0.33
PTGS2 P35354 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2336888 1.00 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL29352459 1.00 LMNA (0.46) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL8369963 0.89 ALDH1A1 (0.39) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL441363 0.89 TYR (0.40) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL29486483 0.89 TYR (0.40) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL25162018 0.87 CYP3A4 (0.46) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL4669769 0.87 ADRB2 (0.45) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL16351136 0.87 TRPA1 (0.50) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL598134 0.83 LMNA (0.65) LMNAPTGS1TRPA1CACNA1CALDH1A1
SCHEMBL11876302 0.82 LMNA (0.34) LMNAPTGS1TRPA1CACNA1CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117577939-A Electrolyte suitable for alloy negative electrode and lithium ion battery 宁波大学 2024-02-20 CN disclosed
US-11724978-B2 Method for oxidizing a 1,1,-bis-(3,4-dimethylphenyl)-alkane to 3,3′,4,4′-benzophenone tetracarboxylic acid EVONIK FIBRES GMBH (AT) 2023-08-15 US disclosed
EP-3838883-B1 METHOD FOR OXIDIZING A 1,1-BIS-(3,4-DIMETHYLPHENYL)-ALKANE TO 3,3',4,4'-BENZOPHENONE TETRACARBOXYLIC ACID EVONIK FIBRES GMBH (AT) 2023-07-12 EP disclosed