Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 5/20 | 0.35 |
| ▸ | ARG2 | P78540 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697372 | 0.72 | LMNA (0.36) | MEN1KMT2AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL28230110 | 0.71 | L3MBTL1 (0.33) | MEN1KMT2AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL8827280 | 0.71 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9697223 | 0.70 | LMNA (0.35) | MEN1KMT2AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL1954054 | 0.70 | ALDH1A1 (0.41) | ARG1ARG2MEN1KMT2AALDH1A1 | |
| SCHEMBL4637127 | 0.70 | ALDH1A1 (0.41) | ARG1ARG2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28286231 | 0.69 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL3661207 | 0.68 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9698366 | 0.68 | L3MBTL1 (0.40) | MEN1KMT2AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL28230111 | 0.68 | ALDH1A1 (0.33) | MEN1KMT2AL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879859-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006124875-A2 | DIARYLSULFONE SULFONAMIDES AND USE THEROF | WYETH (US) | 2006-11-23 | — | — | WO | disclosed |