Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638436 | 0.81 | RAB9A (0.61) | POLBMAPTALDH1A1RAB9A | |
| SCHEMBL4640537 | 0.81 | POLB (0.53) | POLBMAPTALDH1A1PAX8 | |
| SCHEMBL4640324 | 0.80 | POLB (0.52) | POLBMAPTEGFRALDH1A1PAX8 | |
| SCHEMBL4669963 | 0.79 | POLB (0.63) | POLBMAPTALDH1A1PAX8NPC1 | |
| SCHEMBL4638446 | 0.77 | NPC1 (0.51) | POLBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL16146240 | 0.76 | POLB (0.63) | POLBMAPTALDH1A1PAX8 | |
| SCHEMBL4640689 | 0.75 | BRD4 (0.47) | POLBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4565523 | 0.73 | CHRNA7 (0.49) | POLBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL30791422 | 0.73 | POLB (0.70) | POLBMAPTALDH1A1PAX8 | |
| SCHEMBL4671962 | 0.72 | PDGFRB (0.66) | POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | claimed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | claimed |