Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554012 | 0.85 | PDGFRB (0.48) | PDGFRBKDRMAPTRAB9APOLB | |
| SCHEMBL17669155 | 0.80 | KDR (0.86) | PDGFRBKDRL3MBTL1MAPTMEN1 | |
| SCHEMBL17669148 | 0.79 | KDR (1.00) | PDGFRBKDRL3MBTL1MAPTMEN1 | |
| SCHEMBL11924472 | 0.77 | RAB9A (0.68) | L3MBTL1MAPTMEN1HTTRAB9A | |
| SCHEMBL4640537 | 0.74 | POLB (0.53) | PDGFRBKDRMAPTPOLB | |
| SCHEMBL4640324 | 0.73 | POLB (0.52) | MAPTMEN1KMT2APOLB | |
| SCHEMBL2295426 | 0.73 | MAPT (0.71) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL4638436 | 0.72 | RAB9A (0.61) | MAPTRAB9APOLB | |
| SCHEMBL4669960 | 0.72 | POLB (0.51) | MAPTRAB9APOLB | |
| SCHEMBL4669963 | 0.72 | POLB (0.63) | MAPTMEN1RAB9AKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |