Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927600 | 0.81 | HPGD (0.53) | NPC1RAB9AKMT2AHPGDKDM4E | |
| SCHEMBL4669960 | 0.77 | POLB (0.51) | NPC1RAB9AALDH1A1MAPTPOLB | |
| SCHEMBL4638436 | 0.77 | RAB9A (0.61) | RAB9AALDH1A1MAPTPOLB | |
| SCHEMBL4640537 | 0.77 | POLB (0.53) | PDGFRBKDRALDH1A1MAPTPOLB | |
| SCHEMBL6925963 | 0.77 | ALDH1A1 (0.61) | KMT2AHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL4640324 | 0.76 | POLB (0.52) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL4669963 | 0.75 | POLB (0.63) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4640689 | 0.74 | BRD4 (0.47) | NPC1RAB9APDGFRBKDRALDH1A1 | |
| SCHEMBL4565523 | 0.72 | CHRNA7 (0.49) | NPC1RAB9AKMT2AKDM4EMEN1 | |
| SCHEMBL16146240 | 0.72 | POLB (0.63) | KMT2AMEN1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888063-A1 | ANTIFUNGAL AGENTS | F2G Ltd. (GB) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123145-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2006-11-23 | — | — | WO | disclosed |