Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.50 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.50 |
| ▸ | EIF4A2 | Q14240 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670021 | 1.00 | SERPINA6 (0.51) | SERPINA6LMNAGPBAR1SHBGCYP1A2 | |
| SCHEMBL2010128 | 0.83 | SHBG (0.53) | SERPINA6LMNAGPBAR1SHBGCYP1A2 | |
| SCHEMBL5856182 | 0.83 | SHBG (0.44) | SERPINA6LMNAGPBAR1SHBGCYP3A4 | |
| SCHEMBL5856187 | 0.83 | SHBG (0.44) | SERPINA6LMNAGPBAR1SHBGCYP3A4 | |
| SCHEMBL5609666 | 0.81 | G6PD (0.72) | SERPINA6GPBAR1SHBGCYP1A2CYP3A4 | |
| SCHEMBL20980001 | 0.81 | G6PD (0.47) | SERPINA6LMNAGPBAR1SHBGCYP1A2 | |
| SCHEMBL2510061 | 0.81 | G6PD (0.72) | SERPINA6GPBAR1SHBGCYP1A2CYP3A4 | |
| SCHEMBL21328342 | 0.81 | G6PD (0.72) | SERPINA6GPBAR1SHBGCYP1A2CYP3A4 | |
| SCHEMBL21973841 | 0.81 | G6PD (0.72) | SERPINA6GPBAR1SHBGCYP1A2CYP3A4 | |
| SCHEMBL16226435 | 0.81 | G6PD (0.47) | SERPINA6LMNAGPBAR1SHBGCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223941-B1 | THERAPEUTIC TREATMENTS FOR BLOOD CELL DEFICIENCIES USING SREROIDS | HOLLIS EDEN PHARMACEUTICALS (US) | 2008-11-05 | — | — | EP | disclosed |