Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.53 |
| ▸ | G6PD | P11413 | 3/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.46 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.46 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.46 |
| ▸ | EIF4A2 | Q14240 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887284 | 0.85 | SHBG (0.54) | SHBGG6PDSERPINA6EIF4A3EIF4A1 | |
| SCHEMBL16431616 | 0.83 | G6PD (0.64) | SHBGG6PDSERPINA6LMNAGPBAR1 | |
| SCHEMBL19330943 | 0.83 | G6PD (0.64) | SHBGG6PDSERPINA6LMNAGPBAR1 | |
| SCHEMBL598321 | 0.83 | G6PD (0.64) | SHBGG6PDSERPINA6LMNAGPBAR1 | |
| SCHEMBL598190 | 0.83 | G6PD (0.64) | SHBGG6PDSERPINA6LMNAGPBAR1 | |
| SCHEMBL4670021 | 0.83 | SERPINA6 (0.51) | SHBGG6PDSERPINA6EIF4A3EIF4A1 | |
| SCHEMBL4670022 | 0.83 | SERPINA6 (0.51) | SHBGG6PDSERPINA6EIF4A3EIF4A1 | |
| SCHEMBL5609666 | 0.80 | G6PD (0.72) | SHBGG6PDSERPINA6GPBAR1CYP1A2 | |
| SCHEMBL20980001 | 0.80 | G6PD (0.47) | SHBGG6PDSERPINA6EIF4A3EIF4A1 | |
| SCHEMBL21328342 | 0.80 | G6PD (0.72) | SHBGG6PDSERPINA6GPBAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075701-A2 | METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID | KYTHERA BIOPHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | WO | disclosed |
| US-7960367-B2 | Pregnane steroids and their use in the treatment of CNS disorders | UMECRINE AB (SE) | 2011-06-14 | — | — | US | disclosed |