Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | AOC2 | O75106 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377881 | 1.00 | CYP4F2 (0.44) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL4670326 | 1.00 | CYP4F2 (0.44) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL5643255 | 0.85 | TDP1 (0.45) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL34474882 | 0.82 | AOC2 (0.40) | HPGDAOC2MAOAMAOBAOC3 | |
| SCHEMBL5641733 | 0.79 | FFAR1 (0.50) | LMNAHPGDAOC2MAOAMAOB | |
| SCHEMBL5641735 | 0.79 | FFAR1 (0.50) | LMNAHPGDAOC2MAOAMAOB | |
| SCHEMBL5641729 | 0.79 | FFAR1 (0.50) | LMNAHPGDAOC2MAOAMAOB | |
| SCHEMBL1936446 | 0.77 | CYP4F2 (0.72) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL20028730 | 0.76 | MAPT (0.47) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL30189419 | 0.76 | MAPT (0.47) | MAPTMEN1KMT2ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396936-B1 | Modulators of calcitonin and amylin receptor activity | KEMIA, INC. (US) | 2008-07-08 | — | — | US | disclosed |
| US-20070088163-A1 | Modulators of calcitonin and amylin activity | KEMIA, INC. | 2007-04-19 | — | — | US | disclosed |
| US-7189851-B2 | Condensed heterocyclic compounds as calcitonin agonists | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-13 | — | — | US | disclosed |
| US-20050107419-A1 | Condensed heterocyclic compounds as calcitonin agonists | SMITHKLINE BEECHAM CORPORATION | 2005-05-19 | — | — | US | disclosed |
| WO-2005025504-A2 | MODULATORS OF CALCITONIN AND AMYLIN ACTIVITY | KEMIA, INC. (US) | 2005-03-24 | — | — | WO | disclosed |
| WO-2003076440-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS CALCITONIN AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107419-A1 | Condensed heterocyclic compounds as calcitonin agonists | CALCRL, CALCR, CALCB | CYP4F2 2395/4885CYP4A11 1593/4885MAPT 3734/4885 |
| US-20070088163-A1 | Modulators of calcitonin and amylin activity | CALCRL, CALCR, CALCA | CYP4F2 4327/4885CYP4A11 3527/4885MAPT 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.