SCHEMBL4670841

SCHEMBL4670841

O=C(O)c1cc2cc3cc(C(=O)O)ncc3cc2cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
ASPH Q12797 3/20 0.50
KDM8 Q8N371 2/20 0.50
EGFR P00533 2/20 0.46
P4HTM Q9NXG6 2/20 0.45
P4HA1 P13674 1/20 0.45
MIF P14174 1/20 0.45
ALOX15 P16050 3/20 0.44
TSHR P16473 2/20 0.44
HIF1A Q16665 1/20 0.44
ALDH1A1 P00352 5/20 0.43
KDM6B O15054 1/20 0.43
TET3 O43151 1/20 0.43
KDM4A O75164 1/20 0.43
BBOX1 O75936 1/20 0.43
MAPT P10636 1/20 0.43
KDM5A P29375 1/20 0.43
KDM5C P41229 1/20 0.43
KDM4D Q6B0I6 1/20 0.43
TET2 Q6N021 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31055620 1.00 KDM4E (0.50) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL27821497 0.90 EGFR (0.51) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL9424897 0.89 EGFR (0.58) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL9939383 0.83 SIRT6 (0.47) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL4239950 0.82 KDM4E (0.41) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL1201624 0.82 ALDH1A1 (0.48) KDM4EASPHKDM8P4HTMALOX15
SCHEMBL21635181 0.81 KDM4E (0.46) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL26606764 0.81 KDM4E (0.51) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL8834576 0.81 CSNK2A2 (0.39) KDM4EASPHKDM8EGFRP4HTM
SCHEMBL29746814 0.80 EGLN1 (0.54) KDM4EASPHKDM8EGFRP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11491459-B2 Zeolite-like metal-organic frameworks with ana topology KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2022-11-08 US claimed
US-20210394126-A1 USE OF POLYVINYLPYRROLIDONE IN THE PREPARATION OF ANA-ZMOF THIN FILM MEMBRANES FOR SEPARATION PROCESSES UNIV KING ABDULLAH SCI & TECH (SA) 2021-12-23 US claimed
EP-3860749-A1 USE OF POLYVINYLPYRROLIDONE IN THE PREPARATION OF ANA-ZMOF THIN FILM MEMBRANES FOR SEPARATION PROCESSES King Abdullah University of Science and Technology (SA) 2021-08-11 EP claimed
US-20200391180-A1 ZEOLITE-LIKE METAL-ORGANIC FRAMEWORKS WITH ANA TOPOLOGY UNIV KING ABDULLAH SCI & TECH (SA) 2020-12-17 US claimed
WO-2020070622-A1 USE OF POLYVINYLPYRROLIDONE IN THE PREPARATION OF ANA–ZMOF THIN FILM MEMBRANES FOR SEPARATION PROCESSES KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2020-04-09 WO claimed
US-8415493-B2 Zeolite-like metal organic frameworks (ZMOFS): modular approach to the synthesis of organic-inorganic hybrid porous materials having a zeolite like topology UNIVERSITY OF SOUTH FLORIDA (US) 2013-04-09 US claimed
EP-1877412-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2008-01-16 EP claimed
US-20060287190-A1 Zeolite-like metal organic frameworks (ZMOFS): modular approach to the synthesis of organic-inorganic hybrid porous materials having a zeolite like topology UNIVERSITY OF SOUTH FLORIDA 2006-12-21 US claimed
WO-2006116340-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2006-11-02 WO claimed
US-12017186-B2 Use of polyvinylpyrrolidone in the preparation of ana-ZMOF thin film membranes for separation processes KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) 2024-06-25 US disclosed
US-11491459-B2 Zeolite-like metal-organic frameworks with ana topology KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2022-11-08 US disclosed
US-20210394126-A1 USE OF POLYVINYLPYRROLIDONE IN THE PREPARATION OF ANA-ZMOF THIN FILM MEMBRANES FOR SEPARATION PROCESSES UNIV KING ABDULLAH SCI & TECH (SA) 2021-12-23 US disclosed
EP-3860749-A1 USE OF POLYVINYLPYRROLIDONE IN THE PREPARATION OF ANA-ZMOF THIN FILM MEMBRANES FOR SEPARATION PROCESSES King Abdullah University of Science and Technology (SA) 2021-08-11 EP disclosed
EP-3191220-B1 METHOD FOR OPTIMIZING FUEL FOR AN INTERNAL COMBUSTION ENGINE UNIV KING ABDULLAH SCI & TECH (SA) 2021-05-26 EP disclosed
US-20170246614-A1 FUEL UPGRADING AND REFORMING WITH METAL ORGANIC FRAMEWORK UNIV KING ABDULLAH SCI & TECH (SA) 2017-08-31 US disclosed
EP-3191220-A1 FUEL UPGRADING AND REFORMING WITH METAL ORGANIC FRAMEWORK King Abdullah University Of Science And Technology (SA) 2017-07-19 EP disclosed
US-8415493-B2 Zeolite-like metal organic frameworks (ZMOFS): modular approach to the synthesis of organic-inorganic hybrid porous materials having a zeolite like topology UNIVERSITY OF SOUTH FLORIDA (US) 2013-04-09 US disclosed
EP-1877412-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2008-01-16 EP disclosed
US-20060287190-A1 Zeolite-like metal organic frameworks (ZMOFS): modular approach to the synthesis of organic-inorganic hybrid porous materials having a zeolite like topology UNIVERSITY OF SOUTH FLORIDA 2006-12-21 US disclosed
WO-2006116340-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2006-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200391180-A1 ZEOLITE-LIKE METAL-ORGANIC FRAMEWORKS WITH ANA TOPOLOGY ACIN1, POF1B, HLA-A KDM4E 2690/4885ASPH 2074/4885KDM8 872/4885
US-11491459-B2 Zeolite-like metal-organic frameworks with ana topology ACIN1, POF1B, HLA-A KDM4E 2690/4885ASPH 2074/4885KDM8 872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.