Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670884 | 0.92 | KDM1A (0.35) | HTTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL29808393 | 0.89 | KDM4E (0.31) | HTTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL20565609 | 0.89 | KDM4E (0.31) | HTTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL4670918 | 0.89 | — | — | |
| SCHEMBL20565903 | 0.86 | KDM4E (0.32) | HTTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL7119512 | 0.85 | KDM1A (0.39) | HTTSMN1; SMN2ALDH1A1MEN1LMNA | |
| SCHEMBL20565638 | 0.84 | KDM4E (0.30) | HTTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| Benzene SCHEMBL7253583 | 0.83 | KDM1A (0.36) | HTTSMN1; SMN2ALDH1A1HPGDCYP3A4 | |
| SCHEMBL4673295 | 0.83 | HTT (0.32) | HTTSMN1; SMN2 | |
| SCHEMBL29457328 | 0.82 | GPR84 (0.32) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461330-B1 | 3H-NAPHTHO[2,1-b]-PYRANE DERIVATIVES AND THEIR USE | RODENSTOCK GMBH (DE) | 2008-03-12 | — | — | EP | claimed |
| US-6967249-B2 | Photochromic 3H-naphtho[2,1-b]-pyran compounds and photochromic articles produced therewith | RODENSTOCK GMBH (DE) | 2005-11-22 | — | — | US | claimed |
| US-20040267013-A1 | Photochromic 3H-naphtho[2,1-b]-pyran compounds and photochromic articles produced therewith | RODENSTOCK GMBH | 2004-12-30 | — | — | US | claimed |
| EP-1461330-A1 | 3H-NAPHTHO 2,1-B]-PYRANE DERIVATIVES AND THE USE OF THE SAME | Rodenstock GmbH (DE) | 2004-09-29 | — | — | EP | claimed |
| WO-2003055872-A1 | 3H-NAPHTHO[2,1-B]-PYRANE DERIVATIVES AND THE USE OF THE SAME | RODENSTOCK GMBH (DE) | 2003-07-10 | — | — | WO | claimed |
| EP-1461330-B1 | 3H-NAPHTHO[2,1-b]-PYRANE DERIVATIVES AND THEIR USE | RODENSTOCK GMBH (DE) | 2008-03-12 | — | — | EP | disclosed |
| US-6967249-B2 | Photochromic 3H-naphtho[2,1-b]-pyran compounds and photochromic articles produced therewith | RODENSTOCK GMBH (DE) | 2005-11-22 | — | — | US | disclosed |
| US-20040267013-A1 | Photochromic 3H-naphtho[2,1-b]-pyran compounds and photochromic articles produced therewith | RODENSTOCK GMBH | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267013-A1 | Photochromic 3H-naphtho[2,1-b]-pyran compounds and photochromic articles produced therewith | RB1, TERB1, CRY2 | HTT 473/4885SMN1; SMN2 4501/4885ALDH1A1 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.