Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10529078 | 0.83 | POLB (0.60) | NPC1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL18589087 | 0.83 | ALDH1A1 (0.57) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL30817653 | 0.82 | ALDH1A1 (0.73) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL7479419 | 0.82 | ALDH1A1 (0.73) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL30817652 | 0.82 | ALDH1A1 (0.73) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL15046562 | 0.81 | SMN1; SMN2 (0.62) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL14357435 | 0.79 | KDM4E (0.74) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL17946639 | 0.78 | KMT2A (0.64) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL14095272 | 0.78 | ALDH1A1 (0.51) | NPC1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL3976791 | 0.78 | MEN1 (0.53) | NPC1ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403303-B1 | Methods for the preparation of poly(etherimide)s | GEN ELECTRIC (US) | 2008-08-20 | — | — | EP | disclosed |
| CN-1294180-C | Preparation method of poly (diimide ether) | GEN ELECTRIC (US) | 2007-01-10 | — | — | CN | disclosed |
| US-6881815-B2 | Method for the preparation poly(etherimide)s | GENERAL ELECTRIC COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| CN-1497006-A | Preparation method of poly (diimide ether) | 通用电气公司 | 2004-05-19 | — | — | CN | disclosed |
| US-20040063897-A1 | Method for the preparation poly(etherimide)s | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2004-04-01 | — | — | US | disclosed |
| EP-1403303-A1 | Methods for the preparation of poly(etherimide)s | General Electric Company (US) | 2004-03-31 | — | — | EP | disclosed |
| US-5194566-A | Polyarylene sulfide block copolymers, method for making, and use | GENERAL ELECTRIC COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0293692-A2 | Polyarylene sulfide block copolymers, method for making, and use | GENERAL ELECTRIC COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |
| US-4769424-A | Polyarylene sulfide block copolymers, method for making, and use | GENERAL ELECTRIC COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063897-A1 | Method for the preparation poly(etherimide)s | FHIT, PBRM1, PMAIP1 | NPC1 4848/4885ALDH1A1 1691/4885KDM4E 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.