Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676537 | 0.78 | KDM4E (0.39) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL4671916 | 0.75 | PTGS2 (0.47) | PTGS2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL4671634 | 0.73 | PTGS2 (0.69) | PTGS2 | |
| SCHEMBL4673772 | 0.72 | RAB9A (0.37) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL4731833 | 0.71 | ESR1 (0.38) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL5336400 | 0.71 | MAPT (0.40) | PTGS2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL22164585 | 0.62 | KDM4E (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL1801387 | 0.62 | CDK1 (0.49) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL28271167 | 0.61 | IMPDH2 (0.53) | PTGS2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL28586959 | 0.60 | CCNE2 (0.40) | PTGS2KDM4ENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565456-B1 | 1,2,4-TRIAZOLE DERIVATIVE, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | CJ CHEILJEDANG CORP (KR) | 2008-10-01 | — | — | EP | disclosed |
| US-7230010-B2 | 1,2,4-triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-20040106612-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CHEILJEDANG CORPORATION (KR) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106612-A1 | 1,2,4-Triazole derivative, method for preparing the same, and pharmaceutical composition containing the same | NAT1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP1B1 | PTGS2 3173/4885KDM4E 3268/4885NPC1 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.