Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4671962 | 0.85 | PDGFRB (0.66) | PDGFRBKDRPOLBMAPTRAB9A | |
| SCHEMBL4640324 | 0.77 | POLB (0.52) | POLBMAPTALDH1A1PAX8 | |
| SCHEMBL4246150 | 0.74 | BRAF (0.50) | MAPTRAB9A | |
| SCHEMBL1645548 | 0.72 | MAPT (0.58) | MAPTRAB9AALDH1A1 | |
| SCHEMBL16146240 | 0.71 | POLB (0.63) | POLBMAPTALDH1A1PAX8 | |
| SCHEMBL4669960 | 0.71 | POLB (0.51) | POLBMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL4638436 | 0.71 | RAB9A (0.61) | POLBMAPTRAB9AALDH1A1 | |
| SCHEMBL4565523 | 0.71 | CHRNA7 (0.49) | POLBMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL4640537 | 0.71 | POLB (0.53) | PDGFRBKDRPOLBMAPTALDH1A1 | |
| SCHEMBL4638446 | 0.70 | NPC1 (0.51) | PDGFRBKDRPOLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |