SCHEMBL4672250

SCHEMBL4672250

CC#CCOC(=O)C(C)(C)[O]

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.37
MMP9 P14780 2/20 0.37
MMP2 P08253 1/20 0.37
MMP12 P39900 1/20 0.37
CTSK P43235 1/20 0.34
MMP13 P45452 1/20 0.31
ADAM17 P78536 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4677707 0.85 MMP1 (0.36) MMP1MMP9MMP2MMP12CTSK
SCHEMBL8962568 0.84 PRKCA (0.38) MMP1MMP9MMP2MMP12CTSK
SCHEMBL4672256 0.83 CTSK (0.38) MMP1MMP9MMP2MMP12CTSK
SCHEMBL4680238 0.81 MMP1 (0.36) MMP1MMP9MMP2MMP12CTSK
SCHEMBL19105218 0.81 MMP1 (0.36) MMP1MMP9MMP2MMP12CTSK
SCHEMBL4677710 0.81 MMP1 (0.36) MMP1MMP9MMP2MMP12CTSK
SCHEMBL4680243 0.81 CTSK (0.37) MMP1MMP9MMP2MMP12CTSK
SCHEMBL27863693 0.81 MMP1 (0.39) MMP1MMP9MMP2MMP12CTSK
SCHEMBL27837560 0.78 MMP1 (0.37) MMP1MMP9MMP2MMP12CTSK
SCHEMBL19116958 0.76 MMP1 (0.33) MMP1MMP9MMP2MMP12CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed