Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31231917 | 1.00 | P2RX1 (0.50) | P2RX1TMPRSS4MAOBCES2CES1 | |
| SCHEMBL3932311 | 0.83 | CES2 (0.48) | MAOBCES2CES1ALDH1A1MAOA | |
| SCHEMBL537488 | 0.83 | MAOB (0.58) | MAOBCES2CES1ALDH1A1HTT | |
| SCHEMBL29797486 | 0.83 | MAOB (0.58) | MAOBCES2CES1ALDH1A1HTT | |
| SCHEMBL12608936 | 0.81 | ACMSD (0.75) | CES2CES1ALDH1A1KDM4EHPGD | |
| SCHEMBL29759451 | 0.80 | ACMSD (0.66) | MAOBALDH1A1HTTKDM4EHPGD | |
| SCHEMBL130520 | 0.80 | ACMSD (0.66) | MAOBALDH1A1HTTKDM4EHPGD | |
| SCHEMBL364307 | 0.80 | CES2 (0.68) | MAOBCES2CES1MAOALMNA | |
| SCHEMBL29766689 | 0.80 | CES2 (0.68) | MAOBCES2CES1MAOALMNA | |
| SCHEMBL12206987 | 0.80 | MAOB (0.52) | MAOBHTTMAOAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 654 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118924749-A | Preparation method of chromone amide compound for Alzheimer disease drug | 广西民族大学 | 2024-11-12 | — | — | CN | claimed |
| CN-117778281-A | Recombinant genetic engineering bacterium and preparation method of (R) -2- (1-aminoethyl) -4-fluorophenol | 爱斯特（成都）生物制药股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-114751870-B | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof | 贵州医科大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116790686-A | Method for synthesizing (R) -2- (1-aminoethyl) -4-fluorophenol by biological enzyme method | 中国科学院青岛生物能源与过程研究所 | 2023-09-22 | — | — | CN | claimed |
| CN-112973606-B | Stirring device for preparing 5-fluoro-2-hydroxyacetophenone | 河南科锐化工有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-115302917-A | Metal surface phenolic foam sandwich board for building | 山东北理华海复合材料有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114751870-A | 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof | 贵州医科大学 | 2022-07-15 | — | — | CN | claimed |
| CN-114539042-A | Novel synthesis process of 5-fluoro-2-hydroxyacetophenone | 河南旭瑞新材料科技有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-107586796-B | Synthesis method of (R) -2- (1-aminoethyl) -4-fluorophenol | 暨明医药科技（苏州）有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-113045398-A | Preparation process of 5-fluoro-2-hydroxyacetophenone | 河南科锐化工有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-112973606-A | Stirring device for preparing 5-fluoro-2-hydroxyacetophenone | 河南科锐化工有限公司 | 2021-06-18 | — | — | CN | claimed |
| WO-2021020998-A1 | METHOD FOR PRODUCING ROXADUSTAT | ФАЗЫЛОВ, Марат Феликсович | 2021-02-04 | — | — | WO | claimed |
| CN-1978442-A | Synthesis method of (R, R, R, S)2,2' - [ imino-di (methylene) ] bis- (6-fluoro-3, 4-dihydro-2H-1-benzopyran-2-methanol) nepyrrolel hydrochloride | PHYSICO CHEMICAL TECHNOLOGY IN (CN) | 2007-06-13 | — | — | CN | claimed |
| CN-1629164-A | Chiral drug intermediate and synthesis method and application thereof | TECHNICAL INST PHYSICS & CHEMISTRY CAS (CN) | 2005-06-22 | — | — | CN | claimed |
| US-5897940-A | Ink jet transparencies | XEROX CORPORATION (US) | 1999-04-27 | — | — | US | claimed |
| US-5744273-A | Laminatable backing substrates containing fluoro compounds for improved toner flow | XEROX CORPORATION (US) | 1998-04-28 | — | — | US | claimed |
| JP-2218674-A | — | — | None | — | — | JP | disclosed |
| JP-3017076-A | — | — | None | — | — | JP | disclosed |
| US-4002423-A | Benzofuran derivatives process for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |
| US-3994902-A | Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds | STERLING DRUG INC. (US) | 1976-11-30 | — | — | US | disclosed |