Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 6/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467266 | 0.82 | TACR1 (0.62) | LMNATACR1ACHEBCHE | |
| SCHEMBL385325 | 0.82 | TACR1 (0.62) | LMNATACR1ACHEBCHE | |
| SCHEMBL21241481 | 0.82 | USP2 (0.44) | GPR119 | |
| SCHEMBL6943959 | 0.82 | TACR1 (0.62) | LMNATACR1ACHEBCHE | |
| SCHEMBL104498 | 0.82 | USP2 (0.44) | GPR119 | |
| SCHEMBL28441771 | 0.82 | USP2 (0.44) | GPR119 | |
| Ammonia Solution, Strong SCHEMBL28305195 | 0.81 | USP2 (0.42) | GPR119 | |
| Hydrochloric Acid SCHEMBL10382846 | 0.81 | LMNA (0.64) | LMNATACR1ACHE | |
| Iodide SCHEMBL8816299 | 0.81 | TACR1 (0.61) | LMNATACR1ACHEBCHE | |
| SCHEMBL7489314 | 0.79 | GPR119 (0.43) | TACR1GPR119JAK2JAK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590327-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004058709-A1 | CCR8 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | disclosed |