Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293567 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL4672815 | 0.82 | CYP4F2 (0.44) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL23292898 | 0.82 | CYP4F2 (0.44) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL23581535 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL12121917 | 0.81 | CYP4F2 (0.42) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL23293572 | 0.80 | GAA (0.40) | ALDH1A1LMNAHSD17B10GAAKMT2A | |
| SCHEMBL22356277 | 0.80 | ALOX15 (0.52) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL4678703 | 0.80 | CYP4F2 (0.43) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL6620811 | 0.80 | ABCB11 (0.47) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL26247238 | 0.80 | CYP4F2 (0.43) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347033-A1 | HYDROXY AND (HALO)ALKOXY SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117858875-A | Hydroxy-and (halo) alkoxy-substituted tetrahydrofurans as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022256842-A1 | HYDROXY AND (HALO)ALKOXY SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-12-08 | — | — | WO | disclosed |
| US-11326125-B2 | Isobutyric ester compound having acetoxy group at alpha-position, fragrance composition, and use thereof as fragrance | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-05-10 | — | — | US | disclosed |
| US-11326125-B2 | Isobutyric ester compound having acetoxy group at alpha-position, fragrance composition, and use thereof as fragrance | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-05-10 | — | — | US | disclosed |
| US-20210277326-A1 | ISOBUTYRIC ESTER COMPOUND HAVING ACETOXY GROUP AT ALPHA-POSITION, FRAGRANCE COMPOSITION, AND USE THEREOF AS FRAGRANCE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-09-09 | — | — | US | disclosed |
| US-20210277326-A1 | ISOBUTYRIC ESTER COMPOUND HAVING ACETOXY GROUP AT ALPHA-POSITION, FRAGRANCE COMPOSITION, AND USE THEREOF AS FRAGRANCE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-09-09 | — | — | US | disclosed |
| EP-3816267-A1 | ISOBUTYRIC ESTER COMPOUND HAVING ACETOXY GROUP AT ? POSITION, PERFUME COMPOSITION, AND USE AS PERFUME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-05-05 | — | — | EP | disclosed |
| CN-112313319-A | Isobutyrate compounds having acetoxy group in alpha position, fragrance compositions and use as fragrance | 三菱瓦斯化学株式会社 | 2021-02-02 | — | — | CN | disclosed |
| US-9133210-B2 | Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis | GALAPAGOS NV (BE) | 2015-09-15 | — | — | US | disclosed |
| US-20150045327-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS | GILEAD SCIENCES, INC. | 2015-02-12 | — | — | US | disclosed |
| EP-1095935-B1 | 6-Hydroxy-5,6-dihydrouracils as herbicides | SUMITOMO CHEMICAL CO (JP) | 2008-12-17 | — | — | EP | disclosed |
| EP-1101761-B1 | Process for producing 3-phenyluracil compounds | SUMITOMO CHEMICAL CO (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-11-20 | — | — | US | disclosed |
| US-6586368-B1 | Benzofuran derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| US-6410484-B1 | ACTIVE MATERIAL; CONTROLLING WEEDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6339155-B1 | Process for producing 3-phenyluracil compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-15 | — | — | US | disclosed |
| EP-1101761-A2 | Process for producing 3-phenyluracil compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1095935-A1 | 6-Hydroxy-5,6-dihydrouracils as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | CBR3, CBR1, HAAO | ALDH1A1 1340/4885LMNA 2228/4885HSD17B10 945/4885 |
| US-20150045327-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, ABCB11, ABCC5 | ALDH1A1 506/4885LMNA 3524/4885HSD17B10 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.