Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434186 | 0.86 | MAPT (0.60) | ALDH1A1MAPK1HTTMAPTL3MBTL1 | |
| SCHEMBL1093120 | 0.80 | ALDH1A1 (0.97) | ALDH1A1MAPK1HTTMAPTL3MBTL1 | |
| SCHEMBL4673879 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MAPK1HTTMAPTL3MBTL1 | |
| SCHEMBL2078675 | 0.79 | MAPT (0.72) | ALDH1A1MAPK1MAPTL3MBTL1POLB | |
| SCHEMBL4676953 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPK1HTTMAPTPOLB | |
| SCHEMBL4679344 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPK1HTTMAPTPOLB | |
| SCHEMBL594097 | 0.77 | L3MBTL1 (0.69) | ALDH1A1MAPK1MAPTL3MBTL1POLB | |
| SCHEMBL9684591 | 0.76 | ALDH1A1 (0.74) | ALDH1A1MAPK1HTTMAPTPOLB | |
| SCHEMBL4675601 | 0.76 | ALDH1A1 (0.74) | ALDH1A1MAPK1HTTMAPTL3MBTL1 | |
| SCHEMBL1981534 | 0.76 | ALDH1A1 (0.74) | ALDH1A1MAPK1HTTMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-20050081313-A1 | Novel couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |