Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675976 | 0.78 | PTPN1 (0.39) | NCEH1MAPT | |
| SCHEMBL4783722 | 0.76 | NCEH1 (0.40) | NCEH1MAPT | |
| SCHEMBL4673192 | 0.75 | PTPN1 (0.43) | NCEH1MAPT | |
| SCHEMBL4785214 | 0.75 | NCEH1 (0.38) | NCEH1ALDH1A1MAPT | |
| SCHEMBL4675977 | 0.75 | PTPN1 (0.49) | NCEH1MAPT | |
| SCHEMBL4672473 | 0.75 | PTPN1 (0.51) | NCEH1 | |
| SCHEMBL4781322 | 0.72 | NCEH1 (0.43) | NCEH1ALDH1A1MAPT | |
| SCHEMBL4783542 | 0.71 | NCEH1 (0.41) | NCEH1MAPT | |
| SCHEMBL4673574 | 0.70 | NCEH1 (0.38) | NCEH1ALDH1A1MAPT | |
| SCHEMBL4670378 | 0.70 | PTPN1 (0.40) | NCEH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397341-B1 | 6-(ARYL-AMIDO OR ARYL-AMIDOMETHYL)-NAPHTHALEN-2-YLOXY-ACIDIC DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 (PAI-1) | WYETH CORP (US) | 2008-08-06 | — | — | EP | claimed |