Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680087 | 0.80 | HTT (0.61) | ALDH1A1MAPK1HTTOPRK1SMN1; SMN2 | |
| SCHEMBL4679188 | 0.76 | HTT (0.59) | ALDH1A1MAPK1HTTOPRK1SMN1; SMN2 | |
| SCHEMBL17111542 | 0.74 | CUL4A (0.50) | ALDH1A1MAPK1HTTCUL4AOPRK1 | |
| SCHEMBL17111487 | 0.74 | CUL4A (0.50) | ALDH1A1MAPK1HTTCUL4AOPRK1 | |
| SCHEMBL1093120 | 0.73 | ALDH1A1 (0.97) | ALDH1A1MAPK1HTTOPRK1MAPT | |
| SCHEMBL5754442 | 0.73 | TXNRD1 (0.47) | ALDH1A1MAPK1HTTCUL4ANPY5R | |
| SCHEMBL29512840 | 0.72 | KMT2A (0.46) | ALDH1A1MAPK1HTTCUL4ASMN1; SMN2 | |
| SCHEMBL3288936 | 0.72 | CDK2 (0.46) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL4676953 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPK1HTTOPRK1MAPT | |
| SCHEMBL4679344 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPK1HTTOPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-20050081313-A1 | Novel couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |