Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680087 | 0.96 | HTT (0.61) | HTTMAPK1ALDH1A1NPC1MAPT | |
| SCHEMBL4672777 | 0.81 | ALDH1A1 (0.57) | HTTMAPK1ALDH1A1MAPTHRH3 | |
| SCHEMBL19680556 | 0.79 | OPRK1 (0.49) | HTTMAPK1ALDH1A1NPC1MAPT | |
| SCHEMBL4673093 | 0.76 | ALDH1A1 (0.55) | HTTMAPK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1093120 | 0.76 | ALDH1A1 (0.97) | HTTMAPK1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL26633289 | 0.76 | MAPT (0.63) | HTTMAPK1ALDH1A1NPC1MAPT | |
| SCHEMBL26633283 | 0.76 | MAPT (0.63) | HTTMAPK1ALDH1A1NPC1MAPT | |
| SCHEMBL26633342 | 0.76 | MAPT (0.63) | HTTMAPK1ALDH1A1NPC1MAPT | |
| SCHEMBL4676953 | 0.75 | ALDH1A1 (1.00) | HTTMAPK1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4679344 | 0.75 | ALDH1A1 (1.00) | HTTMAPK1ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| US-7175670-B2 | Couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-20050081313-A1 | Novel couplers of 2,3,5-triaminopyridine and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1457199-A1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-15 | — | — | EP | disclosed |