SCHEMBL467310

SCHEMBL467310

Cc1cc(O)c(C(C)C)cc1I

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.59
TRPA1 O75762 2/20 0.47
CHRM1 P11229 1/20 0.47
SLC6A2 P23975 1/20 0.47
ADRA1A P35348 1/20 0.47
HTR2B P41595 1/20 0.47
GABRA1 P14867 2/20 0.45
GABRB2 P47870 2/20 0.45
GABRB1 P18505 1/20 0.45
PKM P14618 3/20 0.45
CYP1A2 P05177 4/20 0.44
CYP2D6 P10635 3/20 0.44
MAPK1 P28482 1/20 0.44
MAPT P10636 5/20 0.41
KMT2A Q03164 3/20 0.41
CYP3A4 P08684 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2C9 P11712 2/20 0.41
ALOX15 P16050 2/20 0.41
HIF1A Q16665 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29538596 1.00 LMNA (0.59) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL5508810 0.94 LMNA (0.58) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL29872559 0.81 LMNA (0.68) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL214157 0.81 LMNA (0.68) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL24034824 0.79 GABRA1 (0.39) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL20150139 0.79 GABRA1 (0.39) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL30213582 0.79 LMNA (0.65) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL1245089 0.79 LMNA (0.65) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL69082 0.79 LMNA (0.65) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL9556365 0.79 LMNA (0.65) LMNATRPA1CHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3263145-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2021-01-20 EP claimed
US-20200179300-A1 Topical Formulation Cures and Heals a Variety of Skin Conditions Including Ulcers, Decubitus Ulcers, Cancer, Abrasions and other Conditions and also accelerates the curing and healing of those Conditions URBAN JOSEPH (US) 2020-06-11 US claimed
US-9872941-B2 Antimicrobial compositions and methods for locking catheters BECTON, DICKINSON AND COMPANY (US) 2018-01-23 US claimed
EP-3263145-A1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS Becton, Dickinson and Company (US) 2018-01-03 EP claimed
EP-1998825-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2017-10-18 EP claimed
US-20170216493-A1 Antimicrobial Compositions and Methods for Locking Catheters BECTON, DICKINSON AND COMPANY 2017-08-03 US claimed
US-9649411-B2 Antimicrobial compositions and methods for locking catheters BECTON, DICKINSON AND COMPANY (US) 2017-05-16 US claimed
US-20160213818-A1 Antimicrobial Compositions and Methods for Locking Catheters BECTON, DICKINSON AND COMPANY 2016-07-28 US claimed
JP-2009528360-A 2009-08-06 JP claimed
EP-1998825-A2 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS Becton, Dickinson and Company, Wagner, Jaconda (US) 2008-12-10 EP claimed
US-20070202177-A1 Antimicrobial Compositions and Methods for Locking Catheters BECTON, DICKINSON AND COMPANY (US) 2007-08-30 US claimed
EP-0854680-B1 Eggs having a low content of polyunsaturated fatty acids SHAPIRA NIVA (IL) 2004-02-11 EP claimed
EP-1344460-A1 Egg having active oxygen eliminating ability and method of producing same Nosan Corporation (JP) 2003-09-17 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
US-6156351-A Eggs with a mixture of antioxidants and low amounts of poly-unsaturated fatty acids SHAPIRA NIVA (IL) 2000-12-05 US claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0854680-A2 EGGS Shapira, Niva (IL) 1998-07-29 EP claimed
WO-1997011596-A2 EGGS SHAPIRA NIVA (IL) 1997-04-03 WO claimed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US claimed
US-4777034-A LONG-LASTING FOOT ANTIPERSPIRANT OLIVIER GEORGES R G (FR) 1988-10-11 US claimed