SCHEMBL4673577

SCHEMBL4673577

CCCCCCOC([O])C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.48
PPARD Q03181 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
GPR84 Q9NQS5 3/20 0.45
NAAA Q02083 1/20 0.45
FFAR1 O14842 1/20 0.45
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
CES2 O00748 1/20 0.44
MAPT P10636 1/20 0.44
DNM1 Q05193 1/20 0.44
PLA2G4B P0C869 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
EPHX1 P07099 1/20 0.42
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4678847 0.98 LCK (0.45) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL4676396 0.91 ALDH1A1 (0.43) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL4672237 0.82
SCHEMBL29408746 0.81 GPR84 (0.47) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL5718514 0.81 HCAR2 (0.48) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL453154 0.81 HCAR2 (0.48) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL31456105 0.81 GPR84 (0.47) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL712622 0.81 HCAR2 (0.48) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL8935618 0.81 HCAR2 (0.48) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL7652872 0.81 HCAR2 (0.48) LCKPPARDZDHHC20ZDHHC2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed