SCHEMBL4676396

SCHEMBL4676396

CCCCOC([O])C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
ATM Q13315 1/20 0.40
CA2 P00918 1/20 0.40
MAPK1 P28482 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
GPR84 Q9NQS5 3/20 0.39
FFAR1 O14842 1/20 0.39
PLA2G4B P0C869 2/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
ALOX5 P09917 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4678847 0.93 LCK (0.45) LCKPPARDZDHHC20ZDHHC2HCAR2
SCHEMBL4673577 0.91 LCK (0.48) LCKPPARDZDHHC20ZDHHC2HCAR2
SCHEMBL4672237 0.86
SCHEMBL284645 0.79 ATM (0.46) ALDH1A1LCKPPARDZDHHC20ZDHHC2
SCHEMBL1196078 0.79 ATM (0.46) ALDH1A1LCKPPARDZDHHC20ZDHHC2
SCHEMBL5079693 0.79 ALDH1A1 (0.44) ALDH1A1LCKPPARDZDHHC20ZDHHC2
SCHEMBL1196777 0.79 ATM (0.46) ALDH1A1LCKPPARDZDHHC20ZDHHC2
SCHEMBL9318505 0.77 ALDH1A1 (0.43) ALDH1A1ATMCA2MAPK1HCAR2
SCHEMBL28479565 0.77 ALDH1A1 (0.43) ALDH1A1LCKPPARDZDHHC20ZDHHC2
SCHEMBL9318736 0.77 ALDH1A1 (0.43) ALDH1A1ATMCA2MAPK1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed