Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2048228 | 1.00 | GRM4 (0.42) | GRM4GRM2GRM3LMNACYP1A2 | |
| SCHEMBL3828109 | 1.00 | GRM4 (0.42) | GRM4GRM2GRM3LMNACYP1A2 | |
| SCHEMBL2048177 | 1.00 | GRM4 (0.42) | GRM4GRM2GRM3LMNACYP1A2 | |
| SCHEMBL296142 | 0.91 | ALDH1A1 (0.44) | LMNATSHRATML3MBTL1ALDH1A1 | |
| SCHEMBL12588188 | 0.87 | OPRK1 (0.41) | CYP2C19S1PR3SGPL1S1PR1ATM | |
| SCHEMBL10299840 | 0.87 | OPRK1 (0.41) | CYP2C19S1PR3SGPL1S1PR1ATM | |
| SCHEMBL6937542 | 0.82 | GRM4 (0.49) | GRM4GRM2GRM3LMNACYP1A2 | |
| SCHEMBL23384404 | 0.81 | GRM4 (0.43) | GRM4GRM2GRM3LMNACYP1A2 | |
| SCHEMBL14144660 | 0.81 | GRM4 (0.45) | GRM4GRM2GRM3LMNACYP1A2 | |
| SCHEMBL14140573 | 0.81 | GRM4 (0.45) | GRM4GRM2GRM3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255367-A1 | Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates | ABBVIE INC. | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255367-A1 | Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates | DDC, DNPEP, AAAS | GRM4 544/4885GRM2 277/4885GRM3 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.