Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3562475 | 0.85 | MRGPRX4 (0.58) | LMNAALDH1A1TDP1HRH2HRH1 | |
| SCHEMBL4671589 | 0.83 | EIF4E (0.42) | ALDH1A1TDP1HRH2HRH1MAOB | |
| SCHEMBL4677512 | 0.83 | KCNH2 (0.53) | LMNAALDH1A1KCNH2MRGPRX4NPC1 | |
| SCHEMBL4671340 | 0.75 | TDP1 (0.45) | LMNAALDH1A1TDP1HRH2HRH1 | |
| SCHEMBL3562225 | 0.75 | MAOB (0.54) | LMNAALDH1A1TDP1HRH2HRH1 | |
| SCHEMBL3557707 | 0.75 | MRGPRX4 (0.57) | MRGPRX4RAB9A | |
| SCHEMBL3555525 | 0.74 | MMP13 (0.46) | ALDH1A1TDP1HRH2HRH1NPC1 | |
| SCHEMBL3566374 | 0.70 | NR4A2 (0.49) | ALDH1A1TDP1HRH2HRH1MAOB | |
| SCHEMBL3569402 | 0.70 | POLB (0.67) | LMNAALDH1A1TDP1PTGESMEN1 | |
| SCHEMBL1423453 | 0.67 | PDE10A (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | claimed |