Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384187 | 0.83 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL15070496 | 0.83 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30761214 | 0.83 | NPC1 (0.59) | RAB9ANPC1SMN1; SMN2HTTTDP1 | |
| SCHEMBL29738597 | 0.83 | SMN1; SMN2 (0.65) | RAB9ANPC1SMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL2989740 | 0.83 | SMN1; SMN2 (0.65) | RAB9ANPC1SMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL7069217 | 0.82 | KMT2A (0.79) | RAB9ANPC1SMN1; SMN2ALOX15HTT | |
| SCHEMBL23405932 | 0.81 | GRM5 (0.64) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5395436 | 0.80 | SMN1; SMN2 (0.66) | RAB9ANPC1SMN1; SMN2ALOX15HTT | |
| SCHEMBL28764679 | 0.80 | L3MBTL1 (0.66) | RAB9ANPC1SMN1; SMN2ALOX15HTT | |
| SCHEMBL29837506 | 0.80 | L3MBTL1 (0.66) | RAB9ANPC1SMN1; SMN2ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644334-B1 | ANTITHROMBOTIC ETHERS | LILLY CO ELI (US) | 2008-01-02 | — | — | EP | disclosed |