SCHEMBL4675609

SCHEMBL4675609

CCCCCOOC(=O)C(C)[O]

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.44
EPHX1 P07099 1/20 0.41
FAAH O00519 2/20 0.41
TSHR P16473 3/20 0.40
DGKA P23743 1/20 0.39
HCAR2 Q8TDS4 2/20 0.39
ZDHHC7 Q9NXF8 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CES2 O00748 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
MAPT P10636 1/20 0.38
RAD52 P43351 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4673156 0.98 NAAA (0.47) NAAAEPHX1FAAHTSHRDGKA
SCHEMBL4676182 0.94 ALDH1A1 (0.45) NAAAEPHX1FAAHTSHRDGKA
SCHEMBL2841961 0.86 NAAA (0.45) NAAAEPHX1TSHRDGKAHCAR2
SCHEMBL4678952 0.85 ALDH1A1 (0.33) NAAAFAAHTSHRDGKAHCAR2
SCHEMBL28001750 0.84 NAAA (0.48) NAAAEPHX1FAAHTSHRDGKA
SCHEMBL11529413 0.82 NAAA (0.47) NAAAEPHX1FAAHTSHRDGKA
SCHEMBL4679363 0.81 NAAA (0.54) NAAAEPHX1FAAHTSHRHCAR2
SCHEMBL28292456 0.81 CA1 (0.50) NAAAEPHX1FAAHTSHRDGKA
SCHEMBL14719802 0.81 NAAA (0.46) NAAAEPHX1TSHRDGKAHCAR2
SCHEMBL4675576 0.80 BLM (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed