Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 6/20 | 0.56 |
| ▸ | PRKCA | P17252 | 5/20 | 0.55 |
| ▸ | PRKACA | P17612 | 3/20 | 0.55 |
| ▸ | PRKACG | P22612 | 3/20 | 0.55 |
| ▸ | PRKACB | P22694 | 3/20 | 0.55 |
| ▸ | PIM1 | P11309 | 2/20 | 0.55 |
| ▸ | PRKCB | P05771 | 4/20 | 0.55 |
| ▸ | PRKCH | P24723 | 3/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 5/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.51 |
| ▸ | QPCT | Q16769 | 3/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.51 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676697 | 0.91 | CAMK2D (0.67) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL4675948 | 0.84 | CAMK2D (0.57) | CAMK2DPRKACAPRKACGPRKACBGSK3B | |
| SCHEMBL4679346 | 0.83 | CAMK2D (0.68) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL2954178 | 0.80 | PRKCA (0.69) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL4679205 | 0.78 | CAMK2D (0.75) | CAMK2DGSK3BQPCTCDK2CCNT1 | |
| SCHEMBL13241407 | 0.78 | CCNT1 (0.70) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL13241411 | 0.77 | CCNT1 (0.76) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL13241410 | 0.76 | CCNT1 (0.74) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL14488702 | 0.75 | PRKCA (0.64) | CAMK2DPRKCAPRKACAPRKACGPRKACB | |
| SCHEMBL4676702 | 0.75 | CAMK2D (0.69) | CAMK2DPRKACAPRKACGPRKACBGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |