SCHEMBL467683

SCHEMBL467683

CO[Si](C)(OC)N1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8075604 1.00 MEN1 (0.32) MEN1HTTRECQLKMT2AATM
SCHEMBL26360833 0.97
SCHEMBL26360839 0.76 KMT2A (0.38) KMT2A
SCHEMBL26073747 0.74
Cyclopropane SCHEMBL3269328 0.74 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL5611439 0.74 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL27516073 0.74 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL203745 0.71 MEN1 (0.30) MEN1HTTRECQLKMT2AATM
SCHEMBL19038499 0.71
SCHEMBL8832416 0.69 MGLL (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2386561-B1 Methods for producing alkoxyhydrosilanes KANEKA CORP (JP) 2016-01-13 EP disclosed
EP-2392600-B1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer KANEKA CORP (JP) 2015-12-23 EP disclosed
EP-2586784-B1 METHOD FOR PRODUCING ALKOXY HYDROSILANE KANEKA CORP (JP) 2015-12-09 EP disclosed
EP-2586783-B1 METHOD FOR PRODUCING ALKOXY HYDROSILANE KANEKA CORP (JP) 2015-08-05 EP disclosed
EP-2586784-A1 METHOD FOR PRODUCING ALKOXY HYDROSILANE Kaneka Corporation (JP) 2013-05-01 EP disclosed
EP-2586783-A1 METHOD FOR PRODUCING ALKOXY HYDROSILANE Kaneka Corporation (JP) 2013-05-01 EP disclosed
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF KANEKACORPORATION (JP) 2012-08-02 US disclosed
EP-2392600-A1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer Kaneka Corporation (JP) 2011-12-07 EP disclosed
EP-2386561-A1 Methods for producing alkoxyhydrosilanes Kaneka Corporation (JP) 2011-11-16 EP disclosed
US-8039142-B2 Battery case SONY CORPORATION (JP) 2011-10-18 US disclosed
US-20110207886-A1 Method for Producing a-hereto-Substituted Alkylhalohydrosilane and Use Thereof KANEKA CORPORATION (JP) 2011-08-25 US disclosed
EP-2308884-A1 METHOD FOR PRODUCING -HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF Kaneka Corporation (JP) 2011-04-13 EP disclosed
EP-1062220-B1 PREPARATION OF SUBSTITUTED (AMINO)DIALKOXYSILANES DEGUSSA CORP (US) 2006-04-05 EP disclosed
US-6114558-A Preparation of alkyl(amino)dialkoxysilanes SIVENTO INC. (US) 2000-09-05 US disclosed
CN-1038331-C Solid catalyst component, process for preparing the same and catalyst for alpha-olefin polymerization HIMONT INC (US) 1998-05-13 CN disclosed
CN-1037106-C Polymetallic catalysts, method of preparing and polymers produced thereby HIMONT INC (US) 1998-01-21 CN disclosed
CN-1108665-A Polymetallic catalysts, method of preparing and polymers produced thereby HIMONT INC (US) 1995-09-20 CN disclosed
CN-1051565-A Method for preparing multi-metal catalyst and polymer produced thereby HIMONT INC (US) 1991-05-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF ARSA, HACL2, AS3MT MEN1 1008/4885HTT 1671/4885RECQL 2389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.