SCHEMBL8075604

SCHEMBL8075604

CO[Si](C)(OC)N1CCCCCCC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467683 1.00 MEN1 (0.32) MEN1HTTRECQLKMT2AATM
SCHEMBL26360833 0.97
SCHEMBL26360839 0.76 KMT2A (0.38) KMT2A
SCHEMBL26073747 0.74
Cyclopropane SCHEMBL3269328 0.74 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL5611439 0.74 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL27516073 0.74 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL203745 0.71 MEN1 (0.30) MEN1HTTRECQLKMT2AATM
SCHEMBL19038499 0.71
SCHEMBL8832416 0.69 MGLL (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165930-A Organosilane compounds MONTELL NORTH AMERICA INC. (US) 2000-12-26 US disclosed
EP-0410443-B1 Organosilane compounds HIMONT INC (US) 1995-01-11 EP disclosed
US-5166340-A Polymerization catalysts, coordination catalysts for olefin polymerization HIMONT INCORPORATED (US) 1992-11-24 US disclosed
EP-0410443-A1 Organosilane compounds MONTELL NORTH AMERICA INC. (US) 1991-01-30 EP disclosed