SCHEMBL203745

SCHEMBL203745

CO[Si](OC)(N1CCCC1)N1CCCC1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5611439 0.97 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL14460061 0.76 HSD11B1 (0.31)
SCHEMBL14460064 0.74 HSD11B1 (0.30)
SCHEMBL26073747 0.73
SCHEMBL26360833 0.73
SCHEMBL27516073 0.73 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
Cyclopropane SCHEMBL3269328 0.73 MEN1 (0.33) MEN1HTTRECQLKMT2AATM
SCHEMBL7209721 0.73 PHGDH (0.37) MEN1RECQLKMT2A
SCHEMBL31211982 0.72 CHRM5 (0.32)
SCHEMBL8075604 0.71 MEN1 (0.32) MEN1HTTRECQLKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528762-B2 Catalyst composition for polyolefin polymers W.R. GRACE & CO.-CONN (US) 2026-01-20 US claimed
US-20250304729-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH LOW EMISSION SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-10-02 US claimed
US-20250304780-A1 PROCESS FOR PREPARING HETEROPHASIC POLYPROPYLENE COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-10-02 US claimed
US-20250289914-A1 PROCESS FOR PREPARING A PROPYLENE COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-09-18 US claimed
US-20250282941-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH LOW HEXANE EXTRACTABLES SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-09-11 US claimed
EP-4522664-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH LOW HEXANE EXTRACTABLES SABIC Global Technologies B.V. (NL) 2025-03-19 EP claimed
US-20250026868-A1 OLEFIN POLYMERIZATION ZIEGLER-NATTA CATALYST COMPONENTS ANDPROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS THEREWITH FORMOSA PLASTICS CORPORATION, USA (US) 2025-01-23 US claimed
CN-119213043-A Process for preparing heterophasic polypropylene compositions SABIC环球技术有限责任公司 2024-12-27 CN claimed
CN-119183458-A Heterophasic polypropylene composition with low hexane extract SABIC环球技术有限责任公司 2024-12-24 CN claimed
CN-119173575-A Heterophasic polypropylene composition with low emissions SABIC环球技术有限责任公司 2024-12-20 CN claimed
US-7141635-B2 Catalyst composition and polymerization process using mixtures of selectivity control agents UNION CARBIDE CHEMICALS AND PLASTICS TECH (US) 2006-11-28 US claimed
US-20060167194-A1 Catalyst composition and polymerization process using mixtures of selectivity control agents W. R. GRACE & CO.-CONN. 2006-07-27 US claimed
EP-1668044-A1 SELF LIMITING CATALYST COMPOSITION WITH DICARBOXYLIC ACID ESTER INTERNAL DONOR AND PROPYLENE POLYMERIZATION PROCESS Dow Global Technologies Inc. (US) 2006-06-14 EP claimed
EP-1668045-A1 CATALYST COMPOSITION WITH MONOCARBOXYLIC ACID ESTER INTERNAL DONOR AND PROPYLENE POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-06-14 EP claimed
EP-1668046-A1 SELF LIMITING CATALYST COMPOSITION AND PROPYLENE POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-06-14 EP claimed
WO-2005035595-A1 SELF LIMITING CATALYST COMPOSITION WITH DICARBOXYLIC ACID ESTER INTERNAL DONOR AND PROPYLENE POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-04-21 WO claimed
WO-2005035596-A1 CATALYST COMPOSITION WITH MONOCARBOXYLIC ACID ESTER INTERNAL DONOR AND PROPYLENE POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-04-21 WO claimed
WO-2005030815-A1 SELF LIMITING CATALYST COMPOSITION AND PROPYLENE POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2005-04-07 WO claimed
EP-1515996-A2 CATALYST COMPOSITION AND POLYMERIZATION PROCESS USING MIXTURES OF ELECTRON DONORS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2005-03-23 EP claimed
WO-2003106512-A2 CATALYST COMPOSITION AND POLYMERIZATION PROCESS USING MIXTURES OF SELECTIVITY CONTROL AGENTS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION ; (US) 2003-12-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528762-B2 Catalyst composition for polyolefin polymers TKT, TCP1, PPT1 MEN1 4056/4885HTT 1280/4885RECQL 4176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.