Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26697146 | 0.83 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL7239176 | 0.80 | MEN1 (0.49) | SMN1; SMN2RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL8337993 | 0.80 | ALDH1A1 (0.55) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL6120372 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL1790735 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL20724273 | 0.79 | ALDH1A1 (0.57) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.78 | POLB (0.78) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL10595799 | 0.78 | POLB (0.73) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL4678478 | 0.77 | MGLL (0.71) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL28702044 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | claimed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |