Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ACP3 | P15309 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677216 | 1.00 | KMT2A (0.58) | KMT2AACP3ALDH1A1HPGDMAPT | |
| SCHEMBL4679414 | 0.85 | KMT2A (0.58) | KMT2AALDH1A1MAPTL3MBTL1PTGS1 | |
| SCHEMBL4679411 | 0.85 | KMT2A (0.58) | KMT2AALDH1A1MAPTL3MBTL1PTGS1 | |
| SCHEMBL29580959 | 0.84 | MMP8 (0.54) | KMT2AACP3ALDH1A1KDM4EAPAF1 | |
| SCHEMBL13721351 | 0.84 | ESR1 (0.50) | KMT2AALDH1A1HPGDKDM4EMMP9 | |
| SCHEMBL7365794 | 0.83 | ACP3 (0.50) | KMT2AACP3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5513822 | 0.83 | ACP3 (0.50) | KMT2AACP3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3823989 | 0.82 | APAF1 (0.55) | KMT2AACP3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6809827 | 0.82 | APAF1 (0.55) | KMT2AACP3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18722284 | 0.82 | APAF1 (0.55) | KMT2AACP3ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945448-B1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-6020496-A | 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |