Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6990543 | 0.99 | LMNA (0.44) | LMNAALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL6987979 | 0.82 | KDM4E (0.59) | LMNAALDH1A1KDM4EPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL6990408 | 0.82 | KMT2A (0.51) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6991722 | 0.81 | KDM4E (0.58) | LMNAALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL4677423 | 0.80 | KDM4E (0.56) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL6988072 | 0.80 | EPHX2 (0.42) | LMNAKDM4EKMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL6993204 | 0.79 | POLB (0.56) | ALDH1A1KDM4EPOLBKMT2AMAPT | |
| SCHEMBL6987336 | 0.79 | CNR1 (0.59) | KDM4EPOLBKMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL6989767 | 0.78 | CNR1 (0.58) | KDM4EPOLBKMT2AMEN1GAA | |
| SCHEMBL6991815 | 0.77 | ALDH1A1 (0.52) | LMNAALDH1A1HPGDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343775-B1 | PIPERAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-06-04 | — | — | EP | disclosed |