Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679271 | 0.91 | CYP1A2 (0.34) | CCR1NTRK1KDM4ELMNADHODH | |
| SCHEMBL4677884 | 0.90 | PPOX (0.41) | KDM4ELMNAMEN1ALDH1A1POLB | |
| SCHEMBL8903541 | 0.89 | CCR1 (0.33) | CCR1NTRK1KDM4EDHODHALDH1A1 | |
| SCHEMBL4682095 | 0.82 | PKM (0.34) | KDM4ELMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL4682523 | 0.81 | PPOX (0.41) | KDM4EDHODHMEN1ALDH1A1PPARG | |
| SCHEMBL4685638 | 0.81 | MPL (0.34) | CCR1NTRK1DHODH | |
| SCHEMBL31448215 | 0.81 | NOTUM (0.37) | CCR1NTRK1LMNACOMTMEN1 | |
| SCHEMBL4681846 | 0.81 | NOTUM (0.37) | CCR1NTRK1LMNACOMTMEN1 | |
| SCHEMBL27413652 | 0.80 | DHODH (0.35) | CCR1DHODHCOMT | |
| SCHEMBL4677674 | 0.80 | PPOX (0.37) | DHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | claimed |