Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405966 | 0.86 | OPRL1 (0.68) | OPRL1OPRM1OPRK1ENPP2CACNA1G | |
| SCHEMBL4683069 | 0.81 | CYP2D6 (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL4909901 | 0.81 | OPRL1 (0.77) | OPRL1OPRM1OPRK1ENPP2CACNA1G | |
| SCHEMBL3633938 | 0.80 | OPRL1 (0.61) | OPRL1OPRM1OPRK1ENPP2 | |
| SCHEMBL3918410 | 0.80 | OPRL1 (0.57) | OPRL1OPRM1OPRK1ENPP2CACNA1G | |
| SCHEMBL13985802 | 0.80 | OPRL1 (0.48) | OPRL1OPRM1OPRK1ENPP2CACNA1G | |
| SCHEMBL3748474 | 0.78 | OPRL1 (0.48) | OPRL1OPRM1OPRK1ENPP2CACNA1G | |
| SCHEMBL3748470 | 0.78 | OPRL1 (0.48) | OPRL1OPRM1OPRK1ENPP2CACNA1G | |
| SCHEMBL4918244 | 0.78 | OPRL1 (0.75) | OPRL1OPRM1OPRK1ENPP2CACNA1G | |
| SCHEMBL27194847 | 0.78 | CACNA1G (0.77) | OPRL1OPRM1CACNA1GCACNA1HCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |