Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ASIC1 | P78348 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679257 | 1.00 | RAB9A (0.36) | RAB9ANPC1LMNAMAPTTOP1 | |
| SCHEMBL4679239 | 0.85 | KDM4E (0.38) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL5411282 | 0.85 | KDM4E (0.38) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL4685195 | 0.81 | ASIC1 (0.47) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL4685196 | 0.81 | ASIC1 (0.47) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL4681613 | 0.76 | MAPT (0.40) | RAB9ANPC1MAPTALDH1A1ASIC1 | |
| SCHEMBL4681607 | 0.76 | MAPT (0.40) | RAB9ANPC1MAPTALDH1A1ASIC1 | |
| SCHEMBL4744870 | 0.76 | TOP1 (0.39) | RAB9ANPC1LMNAMAPTTOP1 | |
| SCHEMBL14445915 | 0.76 | TOP1 (0.39) | RAB9ANPC1LMNAMAPTTOP1 | |
| SCHEMBL14445900 | 0.73 | MAPT (0.42) | RAB9ANPC1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |